circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_101996
Host Gene: hsa-miR-143
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TET2
Associated microRNA: hsa-miR-143
Biological function: The knockdown of hsa_circRNA_101996 dramatically suppressed the cell migration, invasion, and proliferation of GC cells
Molecular mechanism: by sponging to absorb hsa-miR-143 and elevated the expression of TET2
Survival: poor
Supported No.:
 1
Description:

hsa_circRNA_101996 promotes GC development by upregulating MMP2/MMP9 through miR-143/TET2 pathway, which may provide a novel target for GC.
Other information
Title:

Circular RNA Hsa_circRNA_101996 promotes the development of Gastric Cancer via Upregulating Matrix Metalloproteinases-2/Matrix Metalloproteinases-9 through MicroRNA-143/Ten-eleven translocation-2 Pathway.

Journal: J Cancer
Published: 2021/10/19
PubMed ID: 34659556