circRNA basic information
circBase ID: hsa_circ_0000567
Name: hsa_circ_SETD3
Synonym: CircSETD3
Host Gene: hsa-miR-423-3p
 
 
 
Disease basic information
DO ID:
 687
DO name: hepatoblastoma
Disease details: hepatoblastoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: Bim
Associated microRNA: hsa-miR-423-3p
Biological function: circSETD3 overexpression inhibited cell proliferation, viability, migration, epithelial-mesenchymal transition (EMT) and tumorigenesis, and induced cell apoptosis in HB cells
Molecular mechanism: circSETD3 sponged hsa-miR-423-3p to upregulate Bim
Survival: -
Supported No.:
 1
Description:

circSETD3 sponged miR-423-3p to upregulate Bim, resulting in the inhibition of HB development.
Other information
Title:

CircSETD3 (Hsa_circ_0000567) Suppresses Hepatoblastoma Pathogenesis via Targeting the miR-423-3p/Bcl-2-Interacting Mediator of Cell Death Axis.

Journal: Front Genet
Published: 2021/10/19
PubMed ID: 34659347