circRNA basic information
circBase ID: hsa_circ_0016760
Name: -
Synonym: Circ_0016760
Host Gene: hsa-miR-646
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AKT3
Associated microRNA: hsa-miR-646
Biological function: Circ_0016760 interference suppressed cell proliferation, migration, and invasion and promoted the apoptosis of NSCLC cells
Molecular mechanism: via hsa-miR-646/AKT3 signaling
Survival: -
Supported No.:
 6
Description:

Circ_0016760 played an oncogenic role to promote the proliferation, migration, and invasion and restrained the apoptosis of NSCLC cells via miR-646/AKT3 signaling.
Other information
Title:

Circ_0016760 accelerates non-small-cell lung cancer progression through miR-646/AKT3 signaling in vivo and in vitro.

Journal: Thorac Cancer
Published: 2021/10/19
PubMed ID: 34658165