circRNA basic information
circBase ID: hsa_circ_0073181
Name: -
Synonym: Circ_0073181
Host Gene: hsa-miR-548p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PTPRE
Associated microRNA: hsa-miR-548p
Biological function: circ_0073181 knockdown could boost proliferation, migration, invasion and repress apoptosis of HCC cells in vitro
Molecular mechanism: circ_0073181 could regulate PTPRE expression by sponging hsa-miR-548p
Survival: -
Supported No.:
 2
Description:

Circ_0073181 silencing could inhibit HCC cell growth and metastasis partly by regulating the miR-548p/ PTPRE axis, providing a promising therapeutic target for the HCC treatment.
Other information
Title:

Circular RNA circ_0073181 contributes to tumorigenesis by regulating protein tyrosine phosphatase receptor type E via miR-548p in hepatocellular carcinoma.

Journal: Anticancer Drugs
Published: 2021/10/18
PubMed ID: 34657099