circRNA basic information
circBase ID: -
Name: hsa_circ_CD44
Synonym: circCD44
Host Gene: hsa-miR-326, hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SMAD6
Associated microRNA: hsa-miR-326, hsa-miR-330-5p
Biological function: suppressed the proliferation, colony formation, and invasion of GBM cells and inhibited tumor growth in vivo
Molecular mechanism: circCD44 could regulate the expression of SMAD6 via sponging hsa-miR-326 and hsa-miR-330-5p involved in the progression of GBM
Survival: -
Supported No.:
 1
Description:

downregulated expression of circCD44 was found in glioblastoma multiforme (GBM) tissues and GBM primary cells.
Other information
Title:

LRRC4 mediates the formation of circular RNA CD44 to inhibitGBM cell proliferation.

Journal: Mol Ther Nucleic Acids
Published: 2021/10/12
PubMed ID: 34631278