circRNA basic information
circBase ID: -
Name: hsa_circ_PRKDC
Synonym: circPRKDC
Host Gene: hsa-miR-493-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IRS2
Associated microRNA: hsa-miR-493-5p
Biological function: circPRKDC silencing restrained GC cell viability, metastasis, and EMT and suppressed GC tumor growth
Molecular mechanism: via sponging hsa-miR-493-5p and increasing IRS2
Survival: -
Supported No.:
 1
Description:

circPRKDC accelerated GC development via sponging miR-493-5p and increasing IRS2.
Other information
Title:

Circular RNA circPRKDC promotes tumorigenesis of gastric cancer via modulating insulin receptor substrate 2 (IRS2) and mediating microRNA-493-5p.

Journal: Bioengineered
Published: 2021/10/5
PubMed ID: 34605348