circRNA basic information
circBase ID: -
Name: hsa_circ_PIP5K1A
Synonym: circPIP5K1A
Host Gene: hsa-miR-153-3p
 
 
 
Disease basic information
DO ID:
 288
DO name: endometriosis of uterus
Disease details: endometriosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TMSB4X
Associated microRNA: hsa-miR-153-3p
Biological function: Silencing of circPIP5K1A suppressed proliferation, restrained cell cycle, increased cell apoptosis, and decreased migration and invasion in EM cells
Molecular mechanism: circPIP5K1A regulated TMSB4X level via interaction with hsa-miR-153-3p in EM cells
Survival: -
Supported No.:
 1
Description:

circPIP5K1A accelerated EM progression in vitro by activating the TGF-beta signaling pathway via the miR-153-3p/TMSB4X axis, providing a potential clinical target for EM treatment.
Other information
Title:

Circular RNA PIP5K1A (circPIP5K1A) accelerates endometriosis progression by regulating the miR-153-3p/Thymosin Beta-4 X-Linked (TMSB4X) pathway.

Journal: Bioengineered
Published: 2021/9/22
PubMed ID: 34546850