circRNA basic information
circBase ID: -
Name: hsa_circ_SAMD11
Synonym: CircSAMD11
Host Gene: hsa-miR-503
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX4
Associated microRNA: hsa-miR-503
Biological function: Knockdown of circSAMD11 suppressed CC cell proliferation, migration and invasion and accelerated apoptosis
Molecular mechanism: circSAMD11 sponged hsa-miR-503 to modulate SOX4 expression
Survival: -
Supported No.:
 1
Description:

CircSAMD11 contributed to CC progression by regulating miR-503/SOX4 signalling and activating Wnt/beta-catenin pathway, which provides a promising therapeutic target for cervical cancer.
Other information
Title:

CircSAMD11 facilitates progression of cervical cancer via regulating miR-503/SOX4 axis through Wnt/beta-catenin pathway.

Journal: Clin Exp Pharmacol Physiol
Published: 2021/9/22
PubMed ID: 34546569