circRNA basic information
circBase ID: hsa_circ_0001846
Name: -
Synonym: circ_0001846
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: WNT5B
Associated microRNA: hsa-miR-149-5p
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Exosome-mediated transfer of circ_0001846 modulated IL-1beta-induced chondrocyte cell damage by miR-149-5p/WNT5B axis, providing a novel avenue for the therapy of OA.
Other information
Title:

Exosome-mediated circ_0001846 participates in IL-1beta-induced chondrocyte cell damage by miR-149-5p-dependent regulation of WNT5B.

Journal: Clin Immunol
Published: 2021/9/19
PubMed ID: 34536574