circRNA basic information
circBase ID: hsa_circ_0007534
Name: -
Synonym: Circ_0007534
Host Gene: hsa-miR-22-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PROX1
Associated microRNA: hsa-miR-22-3p
Biological function: Circ_0007534 knockdown suppressed the proliferation and motility while induced the apoptosis of glioma cells
Molecular mechanism: through elevating PROX1 expression via targeting hsa-miR-22-3p
Survival: -
Supported No.:
 2
Description:

Circ_0007534 aggravated glioma progression through elevating PROX1 expression via targeting miR-22-3p, which provided new targets for the diagnosis and treatment of glioma.
Other information
Title:

Circ_0007534 Silencing Inhibits the Proliferation, Migration and Invasion and Induces the Apoptosis of Glioma Cells Partly Through Down-Regulating PROX1 Via Elevating miR-22-3p Level.

Journal: Cell Mol Neurobiol
Published: 2021/9/19
PubMed ID: 34536179