circRNA basic information
circBase ID: -
Name: hsa_circ_RHBG
Synonym: circRHBG
Host Gene: hsa-miR-515
 
 
 
Disease basic information
DO ID:
11612
DO name: polycystic ovary syndrome
Disease details: polycystic ovary syndrome
Species: human
Species details: human
Sample type: cell line
Sample type details: KGN, SVOG cells
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC7A11
Associated microRNA: hsa-miR-515
Biological function: Knockdown of circRHBG inhibits KGN and SVOG cell proliferation
Molecular mechanism: circRHBG competes with SLC7A11 to bind to hsa-miR-515-5p
Survival: -
Supported No.:
1
Description:

circRHBG inhibits ferroptosis in PCOS cells through the circRHBG/miR-515-5p/SLC7A11 axis in PCOS.

Other information
Title:

Involvement of ferroptosis in the granulosa cells proliferation of PCOS through the circRHBG/miR-515/SLC7A11 axis.

Journal: Ann Transl Med
Published: 2021/9/18
PubMed ID: 34532485