circRNA basic information
circBase ID: hsa_circ_0075542
Name: hsa_circ_F13A1
Synonym: -
Host Gene: hsa-miR-1197
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: HOXC11
Associated microRNA: hsa-miR-1197
Biological function: overexpression of hsa_circ_0075542 suppressed cell proliferation, reduced migration and invasiveness capabilities, and promoted apoptosis
Molecular mechanism: hsa_circ_0075542 targeted the microRNA-1197 (hsa-miR-1197) homeobox C11 (HOXC11) axis by sponging hsa-miR-1197
Survival: -
Supported No.:
 1
Description:

hsa_circ_0075542 suppressed malignant characteristics and promoted apoptosis in LNCaP and PC3 cells by acting as a competing endogenous RNA of miR-1197. The hsa_circ_0075542/miR-1197 axis might play a role via HOXC11.
Other information
Title:

Circular RNA hsa_circ_0075542 acts as a sponge for microRNA-1197 to suppress malignant characteristics and promote apoptosis in prostate cancer cells.

Journal: Bioengineered
Published: 2021/9/14
PubMed ID: 34515615