circRNA basic information
circBase ID:
hsa_circ_0068631
Name:
hsa_circ_TFRC
Synonym:
-
Host Gene:
-
Disease basic information
DO ID:
1612
DO name:
breast cancer
Disease details:
breast cancer
Species:
human
Species details:
human
Sample type:
tissue, cell line, PDX
Sample type details:
-
circRNA-disease information
Detected method:
Q
S
Detected method confidence
High
Expression pattern:
UP
Associated gene:
EIF4A3/c-Myc
Associated microRNA:
-
Biological function:
Knockdown of hsa_circ_0068631 inhibited the proliferation and migration of BC cells in vitro and in vivo
Molecular mechanism:
hsa_circ_0068631 could recruit EIF4A3 to increase c-Myc mRNA stability.
Survival:
-
Supported No.:
1
Description:
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3.
Other information
Title:
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3.
Journal:
Mol Ther Nucleic Acids
Published:
2021/9/14
PubMed ID:
34513299