circRNA basic information
circBase ID: -
Name: hsa_circ_ASS1
Synonym: circASS1
Host Gene: hsa-miR-1269a
 
 
 
Disease basic information
DO ID:
9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HT29 cell line
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: VASH1
Associated microRNA: hsa-miR-1269a
Biological function: circASS1 overexpression decreased cell proliferation, invasion and migration, but enhanced cell apoptosis in HT29 cells
Molecular mechanism: circASS1 adsorbed hsa-miR-1269a and regulated its expression, and VASH1 was a target protein of hsa-miR-1269a
Survival: -
Supported No.:
1
Description:

circASS1 overexpression inhibited CRC cell proliferation, invasion and migration by regulating miR-1269a/VASH1, which indicated a potential molecular mechanism underlying the pathogenesis of CRC.

Other information
Title:

circASS1 overexpression inhibits the proliferation, invasion and migration of colorectal cancer cells by regulating the miR-1269a/VASH1 axis.

Journal: Exp Ther Med
Published: 2021/9/11
PubMed ID: 34504600