circRNA basic information
circBase ID: -
Name: hsa_circ_ABCB10
Synonym: Circ-ABCB10
Host Gene: hsa-miR-128-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB1
Associated microRNA: hsa-miR-128-3p
Biological function: Loss of circ-ABCB10 weakened cell proliferative and invasive abilities, inhibited EMT, and induced apoptosis in CC
Molecular mechanism: Loss of circ-ABCB10 inhibited ZEB1 expression by serving as a sponge of hsa-miR-128-3p in CC cells
Survival: poor
Supported No.:
 1
Description:

circ-ABCB10 depletion inhibits proliferation, invasion and EMT and promotes apoptosis of cervical cancer cells through miR-128-3p/ZEB1 axis and represses CC tumor growth.
Other information
Title:

Circ-ABCB10 knockdown inhibits the malignant progression of cervical cancer through microRNA-128-3p/ZEB1 axis.

Journal: Biol Proced Online
Published: 2021/9/9
PubMed ID: 34493213