circRNA basic information
circBase ID: hsa_circ_0091994
Name: hsa_circ_FLNA
Synonym: cicrRNA_105040
Host Gene: hsa-miR-324-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: AGS, HGC-27 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGA1
Associated microRNA: hsa-miR-324-5p
Biological function: hsa_circ_0091994 knockdown inhibited the viability of AGS and HGC-27 cells by inducing apoptosis
Molecular mechanism: hsa_circ_0091994 knockdown inhibits GC progression by suppressing hsa-miR-324-5p and HMGA1 expression
Survival: poor
Supported No.:
 2
Description:

Hsa_circ_0091994 knockdown inhibited the progression of GC by inhibiting the miR-324-5p/HMGA1 axis.
Other information
Title:

Knockdown of hsa_circ_0091994 constrains gastric cancer progression by suppressing the miR-324-5p/HMGA1 axis.

Journal: Aging (Albany NY)
Published: 2021/9/7
PubMed ID: 34483139