circRNA basic information
circBase ID: -
Name: hsa_circ_CRIM1
Synonym: -
Host Gene: hsa-miR-513
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human OS cell lines (U2OS, SAOS-2, MG-63, 143B), osteoblast cell line (hFOB1.19)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-513
Biological function: circCRIM1 could decrease the migration, invasion, and growth of OS cells
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

our data uncovered a significant role of the circCRIM1/miR-513 pathway in the proliferation, migration, and invasion of OS cell lines and suggested that circCRIM1 may serve as a possible therapeutic target for OS treatment.
Other information
Title:

The circular RNA circCRIM1 inhibits osteosarcoma progression through sponging miR-513.

Journal: Mamm Genome
Published: 2021/9/5
PubMed ID: 34480205