circRNA basic information
circBase ID: hsa_circ_0008360
Name: -
Synonym: circ_0008360
Host Gene: hsa-miR-135b-5p
 
 
 
Disease basic information
DO ID:
 7148
DO name: rheumatoid arthritis
Disease details: rheumatoid arthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: HDAC4
Associated microRNA: hsa-miR-135b-5p
Biological function: Circ_0008360 suppressed the proliferation, migration, and inflammation and promoted apoptosis of RA-FLSs, and circ_0008360 knockdown showed opposite effects
Molecular mechanism: circ_0008360 positively regulated HDAC4 expression by sponging hsa-miR-135b-5p
Survival: -
Supported No.:
 2
Description:

Circ_0008360 inhibited the proliferation, migration, and inflammation and facilitated apoptosis of RA-FLSs by sponging miR-135b-5p and upregulating HDAC4.
Other information
Title:

Circular RNA circ_0008360 Inhibits the Proliferation, Migration, and Inflammation and Promotes Apoptosis of Fibroblast-Like Synoviocytes by Regulating miR-135b-5p/HDAC4 Axis in Rheumatoid Arthritis.

Journal: Inflammation
Published: 2021/9/1
PubMed ID: 34462830