circRNA basic information
circBase ID: -
Name: hsa_circ_DUSP16
Synonym: circDUSP16
Host Gene: hsa-miR-432-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F6
Associated microRNA: hsa-miR-432-5p
Biological function: circDUSP16 knockdown repressed cell proliferation, migration, and invasion and induced apoptosis in CRC
Molecular mechanism: circDUSP16 upregulated E2F6 expression by reducing hsa-miR-432-5p expression
Survival: poor
Supported No.:
 1
Description:

circDUSP16 knockdown suppressed CRC progression by regulating the miR-432-5p/E2F6 axis, suggesting that the circDUSP16/miR-432-5p/E2F6 network may be a potential therapeutic target for CRC.
Other information
Title:

CircRNA DUSP16 Knockdown Suppresses Colorectal Cancer Progression by Regulating the miR-432-5p/E2F6 Axis.

Journal: Cancer Manag Res
Published: 2021/8/31
PubMed ID: 34456589