circRNA basic information
circBase ID: hsa_circ_0040809
Name: hsa_circ_BANP
Synonym: circ_0040809
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: DNMT1
Associated microRNA: hsa-miR-515-5p
Biological function: circ_0040809 silencing inhibits CRC cell proliferation and migration and promotes apoptosis, while circ_0040809 overexpression has the opposite effects
Molecular mechanism: circ_0040809 competitively binds to hsa-miR-515-5p to elevate DNMT1 expression
Survival: -
Supported No.:
 3
Description:

circ_0040809 facilitates CRC cell proliferation and migration, and inhibits apoptosis, through modulating miR-515-5p/DNMT1 axis.
Other information
Title:

Hsa_circ_0040809 regulates colorectal cancer development by upregulating methyltransferase DNMT1 via targeting miR-515-5p.

Journal: J Gene Med
Published: 2021/8/27
PubMed ID: 34438465