circRNA basic information
circBase ID: -
Name: hsa_circ_RPPH1
Synonym: -
Host Gene: hsa-miR-146b-3p
 
 
 
Disease basic information
DO ID:
 3459
DO name: breast carcinoma
Disease details: breast carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F2
Associated microRNA: hsa-miR-146b-3p
Biological function: circ_RPPH1 can accelerate the proliferation, migration and invasion, and promote tumorigenesis and metastasis
Molecular mechanism: circ_RPPH1 acted as ceRNA (competing endogenous RNA) of hsa-miR-146b-3p, so as to reduce the inhibitory role of hsa-miR-146b-3p on its target E2F2
Survival: poor
Supported No.:
 1
Description:

Circ_RPPH1/miR-146b-3p/E2F2 axis can promote the progression of BC.
Other information
Title:

Mediation of circ_RPPH1 on miR-146b-3p/E2F2 pathway to hinder the growth and metastasis of breast carcinoma cells.

Journal: Aging (Albany NY)
Published: 2021/8/26
PubMed ID: 34433131