circRNA basic information
circBase ID: hsa_circ_0084582
Name: -
Synonym: Circ_0084582
Host Gene: hsa-miR-485-3p
 
 
 
Disease basic information
DO ID:
3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: JAG1
Associated microRNA: hsa-miR-485-3p
Biological function: Circ_0084582 knockdown reduced cell proliferation, cell cycle progression, migration, invasion, and angiopoiesis of OS cells
Molecular mechanism: circ_0084582 could affect the JAG1 level by sponging hsa-miR-485-3p
Survival: -
Supported No.:
1
Description:

circ_0084582 functions as a tumorigenic factor in OS via the regulation of miR-485-3p/JAG1 axis.

Other information
Title:

Circ_0084582 Facilitates Cell Growth, Migration, Invasion, and Angiopoiesis in Osteosarcoma via Mediating the miR-485-3p/JAG1 Axis.

Journal: Front Genet
Published: 2021/8/24
PubMed ID: 34421997