circRNA basic information
circBase ID: -
Name: hsa_circ_ASAP1
Synonym: CircASAP1
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RPP25
Associated microRNA: hsa-miR-338-3p
Biological function: knockdown of circASAP1 impeded proliferation, migration, and invasion while induced apoptosis and cell cycle arrest in cervical cancer cells along with repressed tumor growth in vivo
Molecular mechanism: circASAP1 could function as a sponge for hsa-miR-338-3p to increase the expression of RPP25
Survival: -
Supported No.:
 1
Description:

circASAP1 could function as a sponge for miR-338-3p to increase the expression of RPP25, and further regulated proliferation, migration, invasion, apoptosis, and cell cycle program of cervical cancer cells, which might be potential markers for cervical cancer diagnosis.
Other information
Title:

CircASAP1 promotes the development of cervical cancer through sponging miR-338-3p to upregulate RPP25.

Journal: Anticancer Drugs
Published: 2021/8/19
PubMed ID: 34407047