circRNA basic information
circBase ID: -
Name: hsa_circ_NRIP1
Synonym: circNRIP1
Host Gene: hsa-miR-532-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cell lines (SW620, HT-29, HCT116, SW480), human normal colon epithelial cell line (NCM460), 293T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-532-3p
Biological function: promoted CRC cell proliferation, invasion and migration, while it inhibited apoptosis
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 2
Description:

overexpression of circNRIP1 promoted the progression of CRC, while circNRIP1 silencing sensitized CRC cells to 5_FU via sponging miR_532_3p.
Other information
Title:

Knockdown of circNRIP1 sensitizes colorectal cancer to 5_FU via sponging miR_532_3p.

Journal: Oncol Rep
Published: 2021/8/17
PubMed ID: 34396434