circRNA basic information
circBase ID: -
Name: hsa_circ_KIAA1199
Synonym: Circ_KIAA1199
Host Gene: hsa-miR-34c-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MSI1
Associated microRNA: hsa-miR-34c-5p
Biological function: Circ_KIAA1199 downregulation suppressed CRC cell proliferation, survival, migration and invasion
Molecular mechanism: Circ_KIAA1199 positively regulated MSI1 expression by targeting hsa-miR-34c-5p
Survival: -
Supported No.:
 3
Description:

Circ_KIAA1199 functioned as an oncogene to drive the malignant development of CRC by activating MSI1 via competitively targeting miR-34c-5p.
Other information
Title:

Circ_KIAA1199 inhibits MSI1 degradation by targeting miR-34c-5p to drive the malignant cell behaviors and tumor growth of colorectal cancer.

Journal: Anticancer Drugs
Published: 2021/8/14
PubMed ID: 34387591