circRNA basic information
circBase ID: -
Name: hsa_circ_XPO1
Synonym: circXPO1
Host Gene: hsa-miR-23a
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-23a
Biological function: promote cell proliferation, colony formation, and cell invasion
Molecular mechanism: circXPO1 physically targets hsa-miR-23a and negatively regulates its expression
Survival: -
Supported No.:
 1
Description:

circXPO1 promotes prostate cancer progression via targeting miR-23a, thus suggesting the circXPO1/miR-23a axis can be used as a potential therapeutic target for prostate cancer treatment.
Other information
Title:

The Circular RNA circXPO1 Promotes Tumor Growth via Sponging MicroRNA-23a in Prostate Carcinoma.

Journal: Front Oncol
Published: 2021/8/14
PubMed ID: 34386427