circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_102231
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IRTKS
Associated microRNA: -
Biological function: circRNA_102231 knockdown inhibited GC cell proliferation and invasion both in vitro and in vivo
Molecular mechanism: CircRNA_102231 was able to bind to IRTKS, increasing IRTKS protein stability, leading to GC progression
Survival: -
Supported No.:
 1
Description:

CircRNA_102231 was able to bind to IRTKS, increasing IRTKS protein stability, leading to GC progression. Overexpression of IRTKS effectively rescued the reduced cell viability and invasion caused by silencing of circRNA_102231.

Other information
Title:

Upregulated circRNA_102231 promotes gastric cancer progression and its clinical significance.

Journal: Bioengineered
Published: 2021/8/11
PubMed ID: 34374630