circRNA basic information
circBase ID: hsa_circ_0011385
Name: -
Synonym: circ_0011385
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX4
Associated microRNA: hsa-miR-149-5p
Biological function: Knocking down circ_0011385 restrained the multiplication, migration, and invasion of CC cells and induced the apoptosis
Molecular mechanism: Circ_0011385 directly targeted hsa-miR-149-5p, and SOX4 was the target of hsa-miR-149-5p, which could be positively regulated by circ_0011385
Survival: -
Supported No.:
 2
Description:

Circ_0011385 elevates SOX4 expression by targeting miR-149-5p, thus participating in promoting the malignant biological behaviors of CC cells.
Other information
Title:

Circular RNA circ_0011385 promotes cervical cancer progression through competitively binding to miR-149-5p and up-regulating SOX4 expression.

Journal: Kaohsiung J Med Sci
Published: 2021/8/10
PubMed ID: 34369654