circRNA basic information
circBase ID: -
Name: hsa_circ_FOXK2
Synonym: circFOXK2
Host Gene: hsa-miR-370
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: BC cell line (BT-549), HEK293T cells
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: IGF2BP3
Associated microRNA: hsa-miR-370
Biological function: promoted migration and invasion
Molecular mechanism: circFOXK2 could act with IGF2BP3, an RNA-binding protein, and hsa-miR-370 to synergistically promote BC metastasis
Survival: -
Supported No.:
 1
Description:

circFOXK2 functions as a key regulator in BC metastasis, and the role of circFOXK2 on BC metastasis is tightly associated with the involvement of IGF2BP3 and miR-370.
Other information
Title:

CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis.

Journal: Aging (Albany NY)
Published: 2021/7/31
PubMed ID: 34329193