circRNA basic information
circBase ID: hsa_circ_0005105
Name: hsa_circ_SEC24A
Synonym: circ_SEC24A
Host Gene: hsa-miR-26b-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: DNMT3A
Associated microRNA: hsa-miR-26b-5p
Biological function: -
Molecular mechanism: circ_SEC24A and DNMT3A were competitive endogenous RNAs (ceRNAs) for hsa-miR-26b-5p
Survival: -
Supported No.:
 3
Description:

Circ_SEC24A was a promoting factor for IL-1beta-induced OA progression via circ_SEC24A/miR-26b-5p/DNMT3A ceRNA axis.
Other information
Title:

CircRNA circ_SEC24A upregulates DNMT3A expression by sponging miR-26b-5p to aggravate osteoarthritis progression.

Journal: Int Immunopharmacol
Published: 2021/7/30
PubMed ID: 34325283