circRNA basic information
circBase ID: -
Name: hsa_circ_SCARB1
Synonym: circRNA SCARB1
Host Gene: hsa-miR-497
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-497
Biological function: overexpression of circRNA SCARB1 increased the proliferation and migration of HCC cells
Molecular mechanism: by suppressing the maturation of hsa-miR-497
Survival: -
Supported No.:
 1
Description:

circRNA SCARB1 is upregulated in HCC and promotes HCC cell proliferation and migration by suppressing the maturation of miR-497.
Other information
Title:

The Maturation of Tumor Suppressor miR-497 in Hepatocellular Carcinoma is Inhibited by Oncogenic circRNA SCARB1.

Journal: Cancer Manag Res
Published: 2021/7/27
PubMed ID: 34305409