circRNA basic information
circBase ID: hsa_circ_0039053
Name: hsa_circ_ITGAL
Synonym: -
Host Gene: hsa-miR-637
 
 
 
Disease basic information
DO ID:
684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HepG2, SMMC-7721, Huh-7, Hep3B, HCCLM3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: USP21
Associated microRNA: hsa-miR-637
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
1
Description:

hsa_circ_0039053 could be regarded as a competing endogenous RNA (ceRNA) to positively modulate the expression of USP21 combining with miR-637, which provided a potential target in HCC treatment.

Other information
Title:

Identification of hsa_circ_0039053 as an up-regulated and oncogenic circRNA in hepatocellular carcinoma via the miR-637-mediated USP21 activation.

Journal: J Cancer
Published: 2020/10/31
PubMed ID: 33123285