circRNA basic information
circBase ID: -
Name: hsa_circ_DHTKD1
Synonym: circDHTKD1
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GAB1
Associated microRNA: hsa-miR-326
Biological function: circDHTKD1 knockdown was shown to impede OSCC cell growth and metastasis but motivate apoptosis
Molecular mechanism: circDHTKD1 could sponge hsa-miR-326 to alter GAB1 expression
Survival: -
Supported No.:
 1
Description:

circDHTKD1 contributed to OSCC progression in vivo via the miR-326/GAB1 axis.
Other information
Title:

Oncogenic circDHTKD1 promotes tumor growth and metastasis of oral squamous cell carcinoma in vitro and in vivo via upregulating miR-326-mediated GAB1.

Journal: Braz J Med Biol Res
Published: 2021/7/22
PubMed ID: 34287578