circRNA basic information
circBase ID: hsa_circ_0003221
Name: -
Synonym: Circ_0003221
Host Gene: hsa-miR-758-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CPEB4
Associated microRNA: hsa-miR-758-3p
Biological function: Knockdown of circ_0003221 suppressed cell proliferation, migration, invasion, and EMT and induced cell cycle arrest in cervical cancer cells
Molecular mechanism: via modulating hsa-miR-758-3p/CPEB4 axis
Survival: -
Supported No.:
 2
Description:

circ_0003221 acted as a sponge of miR-758-3p to upregulate CPEB4 expression. In addition, circ_0003221 silence also suppressed tumor growth and EMT in vivo.
Other information
Title:

Circular RNA Circ_0003221 Promotes Cervical Cancer Progression by Regulating miR-758-3p/CPEB4 Axis.

Journal: Cancer Manag Res
Published: 2021/7/16
PubMed ID: 34262342