circRNA basic information
circBase ID: hsa_circ_0000326
Name: hsa_circ_TCONS_l2_00004572
Synonym: hsa_circRNA_000543
Host Gene: hsa-miR-567
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZNF268
Associated microRNA: hsa-miR-567
Biological function: Hsa_circ_000543 promoted cell proliferation, colony formation, migration and invasion, as well as inhibited cell apoptosis in CC cells.
Molecular mechanism: directly targeted hsa-miR-567/ZNF268
Survival: poor
Supported No.:
 2
Description:

Hsa_circ_000543 promoted cell proliferation, colony formation, migration and invasion, as well as inhibited cell apoptosis in CC cells. Hsa_circ_000543 directly targeted miR-567/ZNF268 in CC cell lines. In CC tumor tissues and cells, the hsa_circ_000543 expression was negatively correlated with miR-567 expression and showed a positive correlation with ZNF268 expression.

Other information
Title:

Hsa_circRNA_000543 Predicts Poor Prognosis and Promotes Cervical Cancer Cell Progression Through Regulating miR-567/ZNF268 Axis.

Journal: Cancer Manag Res
Published: 2021/7/9
PubMed ID: 34234564