circRNA basic information
circBase ID: -
Name: hsa_circ_TASP1
Synonym: circTASP1
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 9119
DO name: acute myeloid leukemia
Disease details: acute myeloid leukemia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGA2
Associated microRNA: hsa-miR-515-5p
Biological function: knockdown of circTASP1 inhibited proliferation and induced apoptosis
Molecular mechanism: by modulating hsa-miR-515-5p/HMGA2 pathway
Survival: -
Supported No.:
 1
Description:

circTASP1 acts as a sponge for miR-515-5p to regulate HMGA2, thereby promoting proliferation and inhibiting apoptosis during AML progression.
Other information
Title:

Silencing of circTASP1 inhibits proliferation and induces apoptosis of acute myeloid leukaemia cells through modulating miR-515-5p/HMGA2 axis.

Journal: J Cell Mol Med
Published: 2021/7/2
PubMed ID: 34197029