circRNA basic information
circBase ID: -
Name: hsa_circ_MYLK
Synonym: circMELK
Host Gene: hsa-miR-593
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma multiforme
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EphB2
Associated microRNA: hsa-miR-593
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

circMELK was upregulated in GBM, acting as an oncogene and regulating GBM mesenchymal transition and GSC maintenance via sponging of miR-593.
Other information
Title:

circMELK promotes glioblastoma multiforme cell tumorigenesis through the miR-593/EphB2 axis.

Journal: Mol Ther Nucleic Acids
Published: 2021/6/26
PubMed ID: 34168916