circRNA basic information
circBase ID: hsa_circ_0001946
Name: hsa_circ_CDR1
Synonym: ciRS-7, CDR1as
Host Gene: hsa-miR-7a
 
 
 
Disease basic information
DO ID:
 5844
DO name: myocardial infarction
Disease details: myocardial Infarction
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PARP, SP1
Associated microRNA: hsa-miR-7a
Biological function: promotes myocardial infarction
Molecular mechanism: Cdr1as also functioned as a powerful hsa-miR-7a sponge in myocardial cells, and showed regulation on the protective role of hsa-miR-7a in MI injury, involving the function of hsa-miR-7a targets, PARP and SP1.
Survival: -
Supported No.:
 1
Description:

Cdr1as also functioned as a powerful miR-7a sponge in myocardial cells, and showed regulation on the protective role of miR-7a in myocardial infarction (MI) injury, involving the function of miR-7a targets, PARP and SP1.
Other information
Title:

The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression.

Journal: PLoS One
Published: 2016/3/22
PubMed ID: 26998750