circRNA basic information
circBase ID: hsa_circ_0072088
Name: -
Synonym: Circ_0072088
Host Gene: hsa-miR-375
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: JAK2/STAT3 signaling pathway
Associated microRNA: hsa-miR-375
Biological function: promoted the proliferation, migration, and invasion, and inhibited the apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_0072088 can enhance the proliferation, migration, and invasion, and impede apoptosis of HCC cells. Mechanistically, circ_0072088 activates JAK2/STAT3 signaling pathway by serving as a molecular sponge of miR-375.
Other information
Title:

Circ_0072088 promotes progression of hepatocellular carcinoma by activating JAK2/STAT3 signaling pathway via miR-375.

Journal: IUBMB Life
Published: 2021/6/21
PubMed ID: 34148288