circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF124
Synonym: CircZNF124
Host Gene: hsa-miR-199b-5p
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HEC1A, Ishikawa cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC7A5
Associated microRNA: hsa-miR-199b-5p
Biological function: circZNF124 depletion repressed cell proliferation, leucine uptake, migration and invasion
Molecular mechanism: CircZNF124 regulated SLC7A5 expression by binding to hsa-miR-199b-5p
Survival: poor
Supported No.:
 2
Description:

CircZNF124 depletion inhibited EC cell malignancy by miR-199b-5p/SLC7A5 pathway, which demonstrated that circZNF124 had the potential as a therapeutic target for EC.
Other information
Title:

CircZNF124 regulates cell proliferation, leucine uptake, migration and invasion by miR-199b-5p/SLC7A5 pathway in endometrial cancer.

Journal: Immun Inflamm Dis
Published: 2021/6/20
PubMed ID: 34145797