circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: circHIPK3
Host Gene: hsa-miR-448
 
 
 
Disease basic information
DO ID:
10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PC-3, 22Rv1 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MTDH
Associated microRNA: hsa-miR-448
Biological function: promoted the migration, proliferation, and invasion
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
4
Description:

circHIPK3 plays a carcinogenic effect in PCa by regulating the miR-448/MTDH axis, indicating that circHIPK3 may be a potential therapeutic target for PCa.

Other information
Title:

Circular RNA circHIPK3 modulates prostate cancer progression via targeting miR-448/MTDH signaling.

Journal: Clin Transl Oncol
Published: 2021/6/19
PubMed ID: 34142340