circRNA basic information
circBase ID: -
Name: hsa_circ_CSPP1
Synonym: circ-CSPP1
Host Gene: hsa-miR-431
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LASP1
Associated microRNA: hsa-miR-431
Biological function: The knockdown of circ-CSPP1 attenuated cell proliferation, migration, invasion and promoted apoptosis in vitro and weakened tumor growth in vivo
Molecular mechanism: hsa-miR-431/LASP1 axis
Survival: -
Supported No.:
 3
Description:

Our present study identified the oncogenic role of circ-CSPP1 in CRC partially by the modulation of the miR-431/LASP1 axis, providing evidence for circ-CSPP1 as a promising biomarker for CRC management.
Other information
Title:

Identification of circRNA circ-CSPP1 as a potent driver of colorectal cancer by directly targeting the miR-431/LASP1 axis.

Journal: Open Life Sci
Published: 2021/6/15
PubMed ID: 34124372