circRNA basic information
circBase ID: -
Name: hsa_circ_PUM1
Synonym: CircPUM1
Host Gene: hsa-miR-590-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: METTL3
Associated microRNA: hsa-miR-590-5p
Biological function: CircPUM1 knockdown suppressed cell proliferation, cell cycle and glycolysis in vitro
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircPUM1 promoted NSCLC tumor growth and glycolysis through sequestering miR-590-5p and up-regulating METTL3, providing an improved understanding of NSCLC tumorigenesis and a potential therapeutic target for NSCLC therapy.
Other information
Title:

CircPUM1 promotes cell growth and glycolysis in NSCLC via up-regulating METTL3 expression through miR-590-5p.

Journal: Cell Cycle
Published: 2021/6/8
PubMed ID: 34097560