circRNA basic information
circBase ID: -
Name: hsa_circ_HECTD1
Synonym: CircHECTD1
Host Gene: hsa-miR-320-5p
 
 
 
Disease basic information
DO ID:
3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: C6, U87, HEK-293T cells lines
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC2A1
Associated microRNA: hsa-miR-320-5p
Biological function: CircHECTD1 expression led to the promotion of proliferation and migration of GBM cells
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

the circHECTD1-miR-320-5p-SLC2A1 regulatory pathway promoted the progression of GBM, suggesting that circHECTD1 may be a therapeutic target for GBM.

Other information
Title:

CircHECTD1 Regulates Cell Proliferation and Migration by the miR-320-5p/SLC2A1 Axis in Glioblastoma Multiform.

Journal: Front Oncol
Published: 2021/6/4
PubMed ID: 34079759