circRNA basic information
circBase ID: hsa_circ_0001666
Name: -
Synonym: Circ_0001666
Host Gene: hsa-miR-620
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal breast epithelial cell line (MCF-10A), BC cell lines (MDA-MB-231, MDA-MB-453, BT20, MCF-7, SK-BR-3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: WNK2
Associated microRNA: hsa-miR-620
Biological function: Overexpressed circ_0001666 inhibited the proliferation, migration, invasion, while promoted apoptosis and tumor growth of BC in vitro or in vivo
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_0001666 hindered the progression of BC via miR-620/WNK2 axis.
Other information
Title:

Circ_0001666 affects miR-620/WNK2 axis to inhibit breast cancer progression.

Journal: Genes Genomics
Published: 2021/6/2
PubMed ID: 34061329