circRNA basic information
circBase ID: -
Name: hsa_circ_RPL23A
Synonym: -
Host Gene: hsa-miR-1233
 
 
 
Disease basic information
DO ID:
 4467
DO name: clear cell renal cell carcinoma
Disease details: clear cell renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal kidney epithelial cell line (HK-2), ccRCC cell lines (786-O, 769-P, CAKI-1, A498)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ACAT2
Associated microRNA: hsa-miR-1233
Biological function: The elevated circ_RPL23A suppressed cell cycle progression, proliferation, migration and invasion but promoted apoptosis in ccRCC cells
Molecular mechanism: upregulating ACAT2 expression by competitively binding hsa-miR-1233
Survival: -
Supported No.:
 1
Description:

Circ_RPL23A inhibited ccRCC progression by upregulating ACAT2 expression by competitively binding miR-1233.
Other information
Title:

Circ_RPL23A acts as a miR-1233 sponge to suppress the progression of clear cell renal cell carcinoma by promoting ACAT2.

Journal: J Bioenerg Biomembr
Published: 2021/5/27
PubMed ID: 34036483