circRNA basic information
circBase ID: -
Name: hsa_circ_sirt1
Synonym: circ-sirt1
Host Gene: hsa-miR-132-3p, hsa-miR-212-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BGC-823 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: sirt1
Associated microRNA: hsa-miR-132-3p, hsa-miR-212-3p
Biological function: the proliferation, migration, and invasion activities of BGC-823 cells were inhibited by circ-sirt1 overexpression or miR-132-3p/miR-212-3p knockdown, respectively
Molecular mechanism: by sponging hsa-miR-132-3p/hsa-miR-212-3p and upregulating sirt1 expression
Survival: -
Supported No.:
 1
Description:

circ-sirt1 inhibited tumor growth and invasion probably by sponging miR-132-3p/miR-212-3p and upregulating sirt1 expression in GC.
Other information
Title:

Circ-sirt1 inhibits growth and invasion of gastric cancer by sponging miR-132-3p/miR-212-3p and upregulating sirt1 expression.

Journal: Neoplasma
Published: 2021/5/27
PubMed ID: 34034499