circRNA basic information
circBase ID: -
Name: hsa_circ_TPCN
Synonym: circTPCN
Host Gene: hsa-miR-634
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Hela, C33A
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: mTOR
Associated microRNA: hsa-miR-634
Biological function: Knockdown of circTPCN significantly suppressed proliferation, migration, and invasion and increased apoptosis of cervical cancer cells in vitro
Molecular mechanism: acted as a sponge of hsa-miR-634 to enhance mTOR expression
Survival: -
Supported No.:
 1
Description:

the circTPCN/miR-634/mTOR regulatory pathway might be involved in cervical cancer tumorigenesis, and circTPCN is a potential therapeutic target in cervical cancer.
Other information
Title:

Profiling of circular RNAs and circTPCN/miR-634/mTOR regulatory pathway in cervical cancer.

Journal: Genomics
Published: 2021/5/25
PubMed ID: 34029698