circRNA basic information
circBase ID: hsa_circ_0006948
Name: hsa_circ_FNDC3B
Synonym: -
Host Gene: hsa-miR-3612
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal esophageal squamous cell line (HET-1A), ESCC cell lines (TE-1, KYSE30, EC109)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LASP1
Associated microRNA: hsa-miR-3612
Biological function: circ_0006948 could act as a sponge of miR-3612 to regulate LASP1 expression
Molecular mechanism: circ_0006948 could act as a sponge of hsa-miR-3612 to regulate LASP1 expression
Survival: -
Supported No.:
 4
Description:

Circ_0006948 boosted ESCC progression partly by regulating the miR-3612/LASP1 axis, providing an underlying therapeutic target for the ESCC treatment.
Other information
Title:

Circular RNA circ_0006948 Promotes Esophageal Squamous Cell Carcinoma Progression by Regulating microRNA-3612/LASP1 Axis.

Journal: Dig Dis Sci
Published: 2021/5/24
PubMed ID: 34024023