circRNA basic information
circBase ID: -
Name: hsa_circ_GLIS3
Synonym: circGLIS3
Host Gene: hsa-miR-449c-5p
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: cell line
Sample type details: U251, LN229, NHAs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GLIS3
Associated microRNA: hsa-miR-449c-5p
Biological function: proliferation and apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circGLIS3 could promote proliferation and inhibit apoptosis of GBM cells via targeting miR-449c-5p/GLIS3/CAPG axis in vitro.
Other information
Title:

A circular RNA derived from GLIS3 accelerates the proliferation of glioblastoma cells through competitively binding with miR-449c-5p to upregulate CAPG and GLIS3.

Journal: BMC Neurosci
Published: 2022/9/17
PubMed ID: 36114444